First of all, I just wanted to say how much I love Photoshop CS4. It runs like butter on my iMac in ways CS3 (and definitely CS2) never did.
Anyway, a recent annoyance had been taking away precious seconds in my workflow. At one point I had turned on the grid to lay stuff out, and from then on all documents would open with the grid showing. Hitting cmd-H or View>Show Extras (uncheck) would get rid of it, but when opening and closing a lot of documents, having to do it every time is a huge pain.
Eventually I could handle no more used our good friend google, which brought us to this message board post, which gave the following solutions:
The Solution:
01. Open any picture
02. Then View > Show > Slices
03. Click on the Slices and that’s it problem solved
Thank you, demon9991!

Didn’t work for me, but I’m in CS3. is there anything else I need to do after clicking on the slices.
if that doesn’t work try unticking ‘show transform controls’ in the toolbar when you have the pointer selected.
Stumbled upon this, trying to workout the same problem. Didn’t solve it by your way, but you were really close
Instead of selecting Slices in the Show menu, Deselect the Grid (cmd+’ on Mac, Ctrl+’ on Windows).
PS. Tried this on CS3 and CS4, but haven’t tested on CS5.
Worked awesome, Thanks!
It works on CS5… Thanks for the tip…
Best Regards,
Richard Wendrock
tnx
Thanks you so much … great tip
Awesome thanks for that CS5 confirmed working!
Ctl+ worked for me… Many thanks